Functional and biological characterization of <i>Lactobacillus plantarum</i> with isatin for use as probiotics for therapeutic options

In our study, the functional and biological properties of the developed probiotic formulations containing <i>Lactobacillus plantarum</i> and isatin (<i>Couroupita guianensis</i>) have been evaluated. The developed probiotic formulations have demonstrated remarkable antioxidant, antimicrobial, and cholesterol-lowering properties (67.3 ± 0.57%). In addition, they exhibit high survivability in simulated oral fluid (98.8%). Furthermore, extracellular enzyme production iterates other health attributes of probiotic formulations to the human system by improving the utilization of nutrients in the intestine. In sum, the developed probiotic formulations have unveiled probiotic functions and safer applications, which could pave the way to develop functional foods or lead compounds for drug discovery.