Design and interaction mechanism of novel SIRT1 inhibitors for the treatment of hepatocellular carcinoma
Silent information regulator sirtuin 1 (SIRT1) is a niacinamide adenine dinucleotide (NAD)-dependent histone deacetylase and a promising target for the treatment of hepatocellular carcinoma (HCC).
Authors
- Jing Luo (ORCID: https://orcid.org/0000-0001-5821-5846)
- Qiao Fu (ORCID: https://orcid.org/0000-0001-7151-6977)
- Juan Wang
- Xiaomeng Wang (ORCID: https://orcid.org/0000-0002-3398-5745)
- Yan Yang (ORCID: https://orcid.org/0000-0001-6227-5235)
- Zhenxing Yu (ORCID: https://orcid.org/0000-0002-3852-7815)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Army Medical University (CN)
- Chongqing University of Technology (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4nj04822a
- Citations
- 2
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 3.01