Diagnostic Performance of Combined Conventional CT Imaging Features and Radiomics Signature in Differentiating Grade 1 Tumors from Higher-Grade Pancreatic Neuroendocrine Neoplasms
Conventional imaging features provided higher specificity, while radiomics offered greater sensitivity for identifying higher-grade tumors. Integrating all three features improved diagnostic accuracy, highlighting their complementary roles. This combined model may serve as a valuable tool for distinguishing higher-grade tumors from G1 PanNETs and potentially guiding patient management.
Authors
- Ralph H. Hruban (ORCID: https://orcid.org/0000-0003-4554-5672)
- Shahab Shayesteh
- Mohammad Yasrab (ORCID: https://orcid.org/0009-0007-8177-097X)
- Alejandra Blanco (ORCID: https://orcid.org/0000-0003-1856-5184)
- Elliot K. Fishman (ORCID: https://orcid.org/0000-0002-2567-1658)
- Florent Tixier (ORCID: https://orcid.org/0000-0002-9668-6574)
- Saeed Ghandili (ORCID: https://orcid.org/0000-0001-6292-3212)
- Felipe Lopez‐Ramirez (ORCID: https://orcid.org/0000-0002-1560-9172)
- Daniel Fadaei Fouladi (ORCID: https://orcid.org/0000-0002-8582-8485)
- Linda Chi Hang Chu (ORCID: https://orcid.org/0000-0001-9729-2756)
- Ammar A. Javed (ORCID: https://orcid.org/0000-0002-5463-5250)
- Satomi Kawamoto (ORCID: https://orcid.org/0000-0002-3577-1388)
Institutions
- Johns Hopkins University (US)
- Cancer Research Center (US)
- Sidney Kimmel Comprehensive Cancer Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3390/cancers17061047
- Citations
- 4
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Lustgarten Foundation