High multiple pregnancy rates after double embryo transfers in human: a retrospective cohort study

This study examined whether it is possible to avoid multiple pregnancies in treatments of assisted reproduction when two embryos are transferred to certain patients. Transferring more than one embryo can increase the chances of pregnancy and live birth but also raises the risk of multiple pregnancies. Multiple pregnancies are linked to health risks for both the mother and the children. Using data from a single clinic, this study explored whether there are specific patients who could benefit from the transfer of two embryos while still having a lower risk of multiple pregnancy. However, the researchers found that DETs consistently lead to high rates of multiple pregnancies, even when factors like the mother's age, embryo quality and overall embryo cohort quality are considered. The researchers concluded that transferring a single embryo remains the safest approach to prevent multiple pregnancies.