Enlargement of Shoulder Muscles in an Older Man
A 70-year-old man with a history of hypertension and chronic migraine presented with 10 months of progressive generalized muscle weakness and stiffness. Physical examination revealed generalized muscle wasting except for hypertrophy of bilateral shoulder muscles, and a deltoid muscle biopsy revealed deposition of amorphous material. What is your diagnosis?
Authors
- Ali Alshehri (ORCID: https://orcid.org/0000-0001-6144-8819)
- Hazzaa Alzahrani (ORCID: https://orcid.org/0000-0002-5596-8807)
- Mohammad Alhomoud (ORCID: https://orcid.org/0000-0003-4552-0109)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- King Faisal Specialist Hospital & Research Centre (SA)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1001/jamaoncol.2025.0071
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00