E2F4 Promotes Malignant Behaviors of Prostate Cancer Through Activating MUC1 Expression Transcriptionally

Our findings revealed that E2F4 silencing led to the suppression of growth and metastasis and the promotion of cell apoptosis of PC cells through reducing MUC1 expression, which offered targeting molecules for PC treatment.

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Publication Details

Journal
Asia-Pacific Journal of Clinical Oncology
Published
2025-03-20
DOI
https://doi.org/10.1111/ajco.14164
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

E2F4 Promotes Malignant Behaviors of Prostate Cancer Through Activating MUC1 Expression Transcriptionally

F. Zeng, Chongjun Shi, Weina Kong, Haichao Yang et al.
Asia-Pacific Journal of Clinical Oncology
Prostate Cancer Treatment and Research
article

E2F4 Promotes Malignant Behaviors of Prostate Cancer Through Activating MUC1 Expression Transcriptionally

F. Zeng, Chongjun Shi, Weina Kong, Haichao Yang, Sheryl S.L. Tan, Long Cheng, Weizhong Yang
article en

Abstract

Our findings revealed that E2F4 silencing led to the suppression of growth and metastasis and the promotion of cell apoptosis of PC cells through reducing MUC1 expression, which offered targeting molecules for PC treatment.

Asia-Pacific Journal of Clinical OncologyVol. 21(5)
Second Affiliated Hospital of Guangzhou Medical University (CN), Huizhou Central People's Hospital (CN), First Affiliated Hospital of Jinan University (CN), Guangzhou Medical University (CN), Huizhou University (CN)
Good health and well-being
Openalex Percentile: Top 92%
Prostate Cancer Treatment and Research
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