Assessment of Nutritional Status and Vitamin D Level in Infants with Cow Milk Protein Allergy Before and After Treatment

Background: Cow's milk allergy (CMA) is the predominant food allergy among babies, with an estimated frequency in developed nations between 0.5 percent and three percent. Aim: This research aimed to evaluate the vitamin D level and nutritional status in babies with cow milk protein allergy before and after treatment. Patients and methods: This observational study has been performed on a total of 30 infants diagnosed with cow’s milk protein allergy (CMPA) and 40 healthy control infants to assess the nutritional status and vitamin D levels in infants diagnosed with CMPA before and after treatment. Results: An insignificant variation has been observed among groups regarding family history of allergy, anthropometric assessment, maternal vitamin D supplementation throughout pregnancy, and EBF time p>0.05. Nonetheless, significant variation has been observed in antibiotic usage in the first triTrimester of life (p < 0.05). Insignificant variations have been discovered in total energy, carbohydrates, proteins, lipids, calcium, 25(OH)D, and phosphate levels (p>0.05). Conclusion: We found insignificant variances among groups in age, sex, gestational age, allergy history, anthropometric assessment, vitamin D supplementation, exclusive breastfeeding time, total energy, carbohydrate, protein, lipids, and calcium levels. However, significant differences were found in delivery type, antibiotic use during the first Trimester, and 25(OH)D and phosphate levels.

Publication Details

Journal
The Egyptian Journal of Hospital Medicine
Published
2025-01-01
DOI
https://doi.org/10.21608/ejhm.2025.416980
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
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article

Assessment of Nutritional Status and Vitamin D Level in Infants with Cow Milk Protein Allergy Before and After Treatment

The Egyptian Journal of Hospital Medicine
Food Allergy and Anaphylaxis Research
article

Assessment of Nutritional Status and Vitamin D Level in Infants with Cow Milk Protein Allergy Before and After Treatment

article en

Abstract

Background: Cow's milk allergy (CMA) is the predominant food allergy among babies, with an estimated frequency in developed nations between 0.5 percent and three percent. Aim: This research aimed to evaluate the vitamin D level and nutritional status in babies with cow milk protein allergy before and after treatment. Patients and methods: This observational study has been performed on a total of 30 infants diagnosed with cow’s milk protein allergy (CMPA) and 40 healthy control infants to assess the nutritional status and vitamin D levels in infants diagnosed with CMPA before and after treatment. Results: An insignificant variation has been observed among groups regarding family history of allergy, anthropometric assessment, maternal vitamin D supplementation throughout pregnancy, and EBF time p>0.05. Nonetheless, significant variation has been observed in antibiotic usage in the first triTrimester of life (p < 0.05). Insignificant variations have been discovered in total energy, carbohydrates, proteins, lipids, calcium, 25(OH)D, and phosphate levels (p>0.05). Conclusion: We found insignificant variances among groups in age, sex, gestational age, allergy history, anthropometric assessment, vitamin D supplementation, exclusive breastfeeding time, total energy, carbohydrate, protein, lipids, and calcium levels. However, significant differences were found in delivery type, antibiotic use during the first Trimester, and 25(OH)D and phosphate levels.

The Egyptian Journal of Hospital MedicineVol. 98(1)
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Food Allergy and Anaphylaxis Research
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Assessment of Nutritional Status and Vitamin D Level in Infants with Cow Milk Protein Allergy Before and After Treatment · The Egyptian Journal of Hospital Medicine (2025) | TGRS Research Map | TGRS