Deep learning-based malignancy prediction in thyroid nodules

Although the vast majority of thyroid nodules are non-cancerous, determining whether or not a nodule is cancerous may be a difficult and time-consuming process that often involves unnecessary surgical events. In addition, we discussed the process of developing a model that might anticipate the presence of cancer in thyroid nodules by including a number of the core demographic and ultrasound parameters. A combined sensitivity and specificity score was used to assess the diagnostic performance, and their accuracy was compared to that of radiologists. The comparison between model prediction and expert evaluation reveals the benefit of our approach over human judgement in predicting thyroid nodule malignancy. The results of the experiments show that the suggested algorithm performs better. Nodules of TI-RADS category 4 were used. The area under the receiver operating characteristic curve in the validation dataset was 0.92 (with accuracy of 0.70, sensitivity of 0.81 and specificity of 0.58).

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Publication Details

Journal
International Journal of Medical Engineering and Informatics
Published
2025-01-01
DOI
https://doi.org/10.1504/ijmei.2025.145041
Primary Topic
AI in cancer detection
Type
article
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article

Deep learning-based malignancy prediction in thyroid nodules

M.S. Maharajan, Leo John Baptist Andrews, T. Senthil Kumar, L. Mohana Sundari
International Journal of Medical Engineering and Informatics
AI in cancer detection
article

Deep learning-based malignancy prediction in thyroid nodules

M.S. Maharajan, Leo John Baptist Andrews, T. Senthil Kumar, L. Mohana Sundari
article en

Abstract

Although the vast majority of thyroid nodules are non-cancerous, determining whether or not a nodule is cancerous may be a difficult and time-consuming process that often involves unnecessary surgical events. In addition, we discussed the process of developing a model that might anticipate the presence of cancer in thyroid nodules by including a number of the core demographic and ultrasound parameters. A combined sensitivity and specificity score was used to assess the diagnostic performance, and their accuracy was compared to that of radiologists. The comparison between model prediction and expert evaluation reveals the benefit of our approach over human judgement in predicting thyroid nodule malignancy. The results of the experiments show that the suggested algorithm performs better. Nodules of TI-RADS category 4 were used. The area under the receiver operating characteristic curve in the validation dataset was 0.92 (with accuracy of 0.70, sensitivity of 0.81 and specificity of 0.58).

International Journal of Medical Engineering and InformaticsVol. 17(2)
Botho University (BW), Regional Research Institute of Unani Medicine (IN), Saveetha University (IN)
Openalex Percentile: Top 98%
AI in cancer detection
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Deep learning-based malignancy prediction in thyroid nodules — M.S. Maharajan, Leo John Baptist Andrews, et al. · International Journal of Medical Engineering and Informatics (2025) | TGRS Research Map | TGRS