Thrombolysis for superior vena cava syndrome post bone marrow transplant: a paediatric experience

Our case highlights timely diagnosis and management of pulmonary embolism (PE) and superior vena cava syndrome in a child with a background of Chediak-Higashi syndrome who underwent a bone marrow transplant, the probable precipitant being concomitant autoimmune haemolytic anaemia. He was successfully managed in paediatric critical care with a catheter-directed tissue-type Plasminogen activator (tPA) thrombolysis without any complications. He is currently 3 years post transplant with good immune reconstitution.