Interferometric near-infrared spectroscopy (iNIRS) at 1060nm
Interferometric near-infrared spectroscopy (iNIRS) measures diffuse light field fluctuations with time-of-flight (TOF) resolution of a few dozen picoseconds but has low throughput, needing long integration times to achieve adequate brain sensitivity. Longer wavelengths in diffuse correlation spectroscopy (DCS) improve throughput due to lower photon energy, less scattering, and higher permissible exposures. Motivated by this work, we investigate iNIRS at 1060 nm and find a 6.2 (+/-2.3) times improvement in autocorrelation SNR over 855 nm and 18 (+/-11) times over 773 nm at TOFs of 800-1000 picoseconds. We conclude that the 1060 nm wavelength significantly improves iNIRS measurements of TOF-resolved speckle fluctuations.
Authors
- Santosh Aparanji (ORCID: https://orcid.org/0009-0004-2459-4322)
- Rabisankar Samanta
- Dibbyan Mazumder
- Oybek Kholiqov (ORCID: https://orcid.org/0000-0002-5705-8161)
- Vivek J. Srinivasan (ORCID: https://orcid.org/0000-0001-9683-1949)
- Drew Hamilton
- Héctor Estrada (ORCID: https://orcid.org/0000-0002-4345-6695)
Publication Details
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1117/12.3043978
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00