Open-Motion: an open source high sensitivity low cost blood flowmeter platform

Open-Motion is an open source diagnostic platform intended to help researchers study tissue blood flow and blood volume in laboratory, pre-clinical, and clinical research settings. The platform is designed to be flexible and re-programmable so that a wide variety of tissue types can be explored, while also enabling researchers to configure constrained operation modes so that trained operators can use the system to complete specified workflows, and entities seeking regulatory approval for specific indications can use realizations of the platform in commercial products. The platform utilizes a pulsed long coherence length laser with a pulse width tuned to maximize the platform’s sensitivity to changes in blood flow. By performing most of the computation on individual cameras instead of in a central computer, an arbitrary number of cameras can be used, making the platform configurable for a wide number of applications.