Prognostic Implications of HPV Cell-Free DNA Serial Testing During Follow-Up of p16 Positive Oropharyngeal Squamous Cell Carcinoma After Curative-Intent Treatment
Post-treatment HPV ddPCR reflected treatment response on imaging and serial testing had high PPV and NPV in detecting recurrent disease.
Authors
- Chris Callaghan (ORCID: https://orcid.org/0000-0003-3334-4152)
- Ashley Hay
- Michael S. Adamowicz (ORCID: https://orcid.org/0000-0002-6407-539X)
- Kate Cuschieri (ORCID: https://orcid.org/0000-0002-2604-3928)
- Timothy J. Aitman (ORCID: https://orcid.org/0000-0002-7875-4502)
- Christelle A. M. Robert (ORCID: https://orcid.org/0000-0003-3415-2371)
- Brendan Conn (ORCID: https://orcid.org/0000-0001-7847-9355)
- Iain J. Nixon (ORCID: https://orcid.org/0000-0002-8919-8783)
- J. Mackenzie (ORCID: https://orcid.org/0000-0002-1773-2684)
- David J. Noble (ORCID: https://orcid.org/0000-0001-6738-2152)
- Victoria Salati
- Lara Baste McKean
- Dilip Srinivasan
- S. Linton
Institutions
- NHS Lothian (GB)
- Western General Hospital (GB)
- Edinburgh Cancer Research (GB)
- Edinburgh Royal Infirmary (GB)
Publication Details
- Journal
- Clinical Oncology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1016/j.clon.2025.103807
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Edinburgh and Lothians Health Foundation
- Chief Scientist Office, Scottish Government Health and Social Care Directorate