Determination of skin-insect repellent icaridin and DEET in human urine using solid-phase extraction and liquid chromatography with tandem mass spectrometry and its application to a sample of Japanese adults
This method was successful in measuring urinary exposure biomarkers of skin-IR, including icaridin and DEET. Moreover, this study presents the first application of biomonitoring of urinary icaridin concentrations after using a commercial product.
Authors
- Isao Saito (ORCID: https://orcid.org/0000-0003-2048-9248)
- Mai Takagi (ORCID: https://orcid.org/0000-0002-9122-3482)
- Nanami Nishihara
- Miyuki Iwai‐Shimada (ORCID: https://orcid.org/0000-0003-4275-548X)
- Jun Ueyama (ORCID: https://orcid.org/0000-0003-0660-2726)
- Satoru Watanabe (ORCID: https://orcid.org/0000-0001-7456-5053)
- Tomohiko Isobe (ORCID: https://orcid.org/0000-0001-9235-1227)
- Yugo Kitahara
- T. Tajima (ORCID: https://orcid.org/0009-0000-8933-1225)
- Mai Hayashi
Institutions
- National Institute for Environmental Studies (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Environmental Health and Preventive Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1265/ehpm.24-00220
- Citations
- 5
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 7.79
Funders
- Environmental Restoration and Conservation Agency
- Japan Society for the Promotion of Science