Asthma and COVID-19 (review)

An analysis and systematization of scientific literature on the combination of asthma and COVID-19 was conducted using the scientific databases PubMed/MEDLINE and eLIBRARY.RU. The data on the relationship between asthma and COVID-19 are shown to be contradictory. The mechanism of inflammation development and its characteristics in the new coronavirus infection are discussed. The significant role of natural killer (NK) cells and T-natural killer (T-NK) cells in the pathogenesis of the disease is emphasized. The importance of the type of inflammation in asthma in the risk of SARS-CoV-2 infection is concluded. Information on the dual nature of the data regarding the use of inhaled corticosteroids in the treatment of asthma in patients with COVID-19 is presented. The authors conclude that the results of current research do not allow a definitive conclusion to be drawn about a higher predisposition to SARS-CoV-2 infection or more severe COVID-19 in asthma patients, nor about the negative impact of COVID-19 on the course and control of asthma.