Asthma as a manifestation of post-COVID syndrome

Introduction. One of the most common complications of the novel coronavirus infection (COVID-19) involves respiratory system disorders, particularly bronchial obstruction. Aim. To highlight the importance of vigilance regarding the onset of respiratory diseases, including asthma, in the post-COVID period. Results. This article describes a clinical case of newly diagnosed severe asthma in a 35-year-old patient following COVID-19. A notable feature of the patient’s condition was prolonged eosinophilia. Sensitization to inhalant allergens was ruled out by a negative Phadiatop ImmunoCAP screening test. Despite receiving a fixed triple combination of an inhaled corticosteroid, a long-acting β 2 agonist, and a long-acting anticholinergic agent, the patient’s disease remained uncontrolled with persistent airway obstruction. A genetically engineered biological therapy was subsequently prescribed, resulting in a marked clinical improvement. Conclusion. This clinical case illustrates a manifestation of post-COVID syndrome—new-onset asthma. Timely diagnosis enables the prompt selection of appropriate therapy, improving the patient’s quality of life and facilitating a return to normal daily activities.

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Publication Details

Journal
Bulletin physiology and pathology of respiration
Published
2025-03-20
DOI
https://doi.org/10.36604/1998-5029-2025-95-126-134
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Asthma as a manifestation of post-COVID syndrome

И. В. Демко, O. S. Kruglova, Е. А. Собко, E. S. Mineeva et al.
Bulletin physiology and pathology of respiration
Respiratory viral infections research
article

Asthma as a manifestation of post-COVID syndrome

И. В. Демко, O. S. Kruglova, Е. А. Собко, E. S. Mineeva, А. Yu. Kraposhina, E.A. Bykhanova, K. I. Chinyakova
article en

Abstract

Introduction. One of the most common complications of the novel coronavirus infection (COVID-19) involves respiratory system disorders, particularly bronchial obstruction. Aim. To highlight the importance of vigilance regarding the onset of respiratory diseases, including asthma, in the post-COVID period. Results. This article describes a clinical case of newly diagnosed severe asthma in a 35-year-old patient following COVID-19. A notable feature of the patient’s condition was prolonged eosinophilia. Sensitization to inhalant allergens was ruled out by a negative Phadiatop ImmunoCAP screening test. Despite receiving a fixed triple combination of an inhaled corticosteroid, a long-acting β 2 agonist, and a long-acting anticholinergic agent, the patient’s disease remained uncontrolled with persistent airway obstruction. A genetically engineered biological therapy was subsequently prescribed, resulting in a marked clinical improvement. Conclusion. This clinical case illustrates a manifestation of post-COVID syndrome—new-onset asthma. Timely diagnosis enables the prompt selection of appropriate therapy, improving the patient’s quality of life and facilitating a return to normal daily activities.

Bulletin physiology and pathology of respiration(95)
Krasnoyarsk State Medical University (RU), Krasnoyarsk Regional Clinical Hospital (RU)
Openalex Percentile: Top 92%
Respiratory viral infections research
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