Investigation of Inflammation Rates (Neutrophil/Lymphocyte) and Hemogram Results in the Stages of Non-Alcoholic Fatty Liver Disease

Introducton: Non-alcoholic fatty liver disease (NAFLD) is a chronic condition characterized by excessive fat accumulation in the liver accompanied by inflammation. This study aims to know the diagnostic value of NLR in stages of NAFLD Methods: A retrospective case-control study was conducted, including 49 NAFLD patients with NAFLD Grade 1, 48 with NAFLD Grade 2, 52 with NAFLD Grade 3, and 103 healthy control (HC) individuals. Neutrophil/Lymphocyte ratios as well as RBC, HGB, HCT, MCHC, MPV, WBC, MCV, MCH, PLT, RDW-SD, RDW-CV, PDW, PCT, NEUT#, LYMPH%, NLR, MONO%, EO%, BASO% values were examined. Results: As the disease stages progressed (G3), a significant decrease (p=0.005*) in MPV values and a significant increase (p0.05), MCH (p>0.05), PDW (p>0.05), PCT (p>0.05), MONO (p>0.05) and EO (p>0.05) parameters. Conclusion: MPV and NLR may be considered as effective biomarkers for monitoring the progression of NAFLD and evaluating the inflammatory status of patients.