The pulmonary valve in tetralogy of Fallot: insights from a necroscopy series

In two-thirds of our hearts with tetralogy of Fallot, the pulmonary valve had two leaflets. Most frequently there were three sinuses. In the setting of a valve with two sinuses, the zone of apposition between the leaflets pointing towards the aorta. Cluster analysis permitted statistically sound segregation of the heart and highlights the importance of delineating these features, specifically the leaflet and sinus morphology, with clinical imaging.

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Publication Details

Journal
Cardiology in the Young
Published
2025-03-20
DOI
https://doi.org/10.1017/s1047951125001398
Primary Topic
Congenital Heart Disease Studies
Type
article
Field-Weighted Citation Impact
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article

The pulmonary valve in tetralogy of Fallot: insights from a necroscopy series

Rohit S. Loomba, Justin T. Tretter, Robert H. Anderson, Diane E. Spicer
1 links
Cardiology in the Young
Congenital Heart Disease Studies
article

The pulmonary valve in tetralogy of Fallot: insights from a necroscopy series

Rohit S. Loomba, Justin T. Tretter, Robert H. Anderson, Diane E. Spicer
article en

Abstract

In two-thirds of our hearts with tetralogy of Fallot, the pulmonary valve had two leaflets. Most frequently there were three sinuses. In the setting of a valve with two sinuses, the zone of apposition between the leaflets pointing towards the aorta. Cluster analysis permitted statistically sound segregation of the heart and highlights the importance of delineating these features, specifically the leaflet and sinus morphology, with clinical imaging.

Cardiology in the YoungVol. 35(5)
Northwestern University (US), Lurie Children's Hospital (US), Cleveland Clinic (US), Johns Hopkins University (US), Johns Hopkins All Children's Hospital (US), Newcastle University (GB)
Openalex Percentile: Top 92%
Congenital Heart Disease Studies
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