Profile of secondary metabolite compounds in sun-dried cubeb (<i>Piper cubeba</i>) leaves using GC-MS (<i>Gas Chromatography-Mass Spectrometry</i>)

Abstract The cubeb plant ( Piper cubeba ) is a medicinal plant widely used to treat various digestive and respiratory tract diseases such as asthma, diarrhea, sore throat, and lungs. This is due to the presence of secondary metabolic compounds in the cubeb plant. Each part of the cubeb plant has medicinal properties apart from the fruit, namely the cubeb leaves. This study aimed to profile the secondary metabolic compounds of sun-dried cubeb leaves. This is because the drying system still depends on the sun. Metabolic compound profile analysis using GC-MS ( Gas Chromatography-Mass Spectrometry ). The method using GC-MS was chosen because many secondary metabolite compounds can be profiled using GC-MS. The profiling result value is taken based on the number of compound match factors &gt;70%. Analysis of metabolic compound results using GC-MS was carried out descriptively. The results of secondary metabolic compound profiling of sun-dried cubeb leaves using 96% ethanol solvent identified 24 compounds and 22 compounds identified with 70% ethanol solvent. The sun-dried cubeb leaves contain various secondary metabolic compounds, including terpenes, alkaloids, and flavonoids, which have potential applications in medicine, food additives, and cosmetics.