[Mechanism of electroacupuncture at "Zusanli"(ST36) in improving cognitive impairment in mice with systemic inflammation based on the α7 nicotinic acetylcholine receptor pathway of hippocampal microglia].
EA at ST36 with low-intensity may improve neuroinflammatory response and systemic inflammatory cognitive dysfunction by increasing the choline level in the hippocampus and reducing the release of inflammatory factors through up-regulating the expression of α7nAChR in hippocampal microglia.
Authors
- Zhifu Wang
- Xiangmei Yu
- Yuting Huang (ORCID: https://orcid.org/0000-0001-9986-5124)
- Yanxiong Ke (ORCID: https://orcid.org/0000-0002-5412-2869)
- Xiaomei Chen (ORCID: https://orcid.org/0000-0001-5099-2990)
- Yanyan Lan (ORCID: https://orcid.org/0000-0002-7811-3262)
- Lina Pang
- Qiuling Huang
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-25
- DOI
- https://doi.org/10.13702/j.1000-0607.20241273
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article