[Effect of moxibustion combined with chemotherapy on immune checkpoints in tumor tissue of breast cancer-bearing mice].
Moxibustion combined with chemotherapy shows more significant effects in inhibiting tumor growth in breast cancer-bearing mice compared to moxibustion or chemotherapy alone. It reduces the expression of PD-1, TIM-3, and CTLA-4 in tumor tissues, suggesting that lowering immune checkpoint expression levels may be one of the mechanisms by which moxibustion combined with chemotherapy drugs treats tumors.
Authors
- F. Zhang (ORCID: https://orcid.org/0000-0002-3675-5697)
- Xinyue Liang (ORCID: https://orcid.org/0000-0002-2126-2347)
- Ji-Juan Li
- Chenxi Zhang (ORCID: https://orcid.org/0000-0002-8940-0902)
- Xiao‐Qi Zhang (ORCID: https://orcid.org/0000-0002-4436-0273)
- Tianyu Gao (ORCID: https://orcid.org/0009-0001-5396-3180)
- Lijia Pan (ORCID: https://orcid.org/0000-0003-3794-9351)
- Chun‐Sheng Jia (ORCID: https://orcid.org/0000-0002-5548-065X)
Institutions
- Hebei University of Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-25
- DOI
- https://doi.org/10.13702/j.1000-0607.20240144
- Citations
- 2
- Primary Topic
- Healthcare and Venom Research
- Type
- article