[Electroacupuncture improves colonic mucosal barrier damage by regulating NLRP3/Caspase-1/GSDMD signaling pathway and inhibiting pyroptosis in ulcerative colitis mice].
EA can protect the intestinal mucosal permeability in UC mice, which may be related to its functions in regulating the NLRP3/Caspase-1/GSDMD axis and inhibiting pyroptosis, thereby alleviating the inflammatory injury of intestinal mucosa.
Authors
- Yi Qu (ORCID: https://orcid.org/0000-0002-9993-8810)
- Jin Lu (ORCID: https://orcid.org/0000-0002-0946-3357)
- T H Wang
- Yanan Xue (ORCID: https://orcid.org/0000-0002-7966-3899)
- Jiazi Dong
- Xinghan Wang (ORCID: https://orcid.org/0000-0002-6831-9056)
- Jidong Liu (ORCID: https://orcid.org/0000-0003-3269-1240)
- Jianbo Wang (ORCID: https://orcid.org/0000-0002-2666-2841)
- Jiahao Zhang (ORCID: https://orcid.org/0000-0003-3073-952X)
- Xinlong Wang (ORCID: https://orcid.org/0000-0002-8137-1692)
- Li Yang (ORCID: https://orcid.org/0000-0002-0220-6200)
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Shenyang University of Technology (CN)
- Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-25
- DOI
- https://doi.org/10.13702/j.1000-0607.20240402
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article