Exploration and validation of biomarkers for Alzheimer's disease based on GEO database
This study not only confirmed the known genes linked to AD but, more significantly, revealed the potential connection between the <i>RBL2</i> gene and AD. Furthermore, it verified a causal link between <i>RBL2</i> and the risk of AD onset. This finding suggests that the <i>RBL2</i> gene could serve as a promising biomarker for the early diagnosis of AD, thereby offering novel avenues for future research and clinical interventions.
Authors
- Zhenhe Zhou (ORCID: https://orcid.org/0000-0002-1334-8335)
- Danting Yang (ORCID: https://orcid.org/0000-0002-5635-6474)
- Y. Gan
- Jian Yin (ORCID: https://orcid.org/0000-0001-9668-3704)
- Jiaojiao Sun
- C. T. Fang
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1016/j.ibneur.2025.03.006
- Citations
- 2
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68