Experimental orthodontic pain drives anxiety state through the induction of alterations to the neuronal architecture in hippocampus
Experimental orthodontic pain drives emotional anxiety through the plasticity changes in decreased neuronal complexity and reduced spine density in ventral hippocampal CA1 in mice.
Authors
- Hong Ai (ORCID: https://orcid.org/0000-0001-7118-2663)
- Shaoqin Tu (ORCID: https://orcid.org/0000-0003-4391-8025)
- Huilin Que (ORCID: https://orcid.org/0009-0001-5638-9233)
- Nan Wei (ORCID: https://orcid.org/0009-0008-8571-4796)
- Jiaming Wei
- Yi Feng (ORCID: https://orcid.org/0000-0002-3952-1351)
- Chau‐kiu Cheung (ORCID: https://orcid.org/0000-0003-3278-1633)
- Zheng Chen (ORCID: https://orcid.org/0000-0002-3505-0396)
- Yuxuan Wang (ORCID: https://orcid.org/0000-0002-1649-6974)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- BMC Neuroscience
- Published
- 2025-03-20
- DOI
- https://doi.org/10.1186/s12868-025-00945-9
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province