Elevated red blood cell folate levels are associated with metabolic dysfunction-associated steatotic liver disease: results from NHANES 2017–2020

These findings suggest that elevated RBC folate levels are independently associated with MASLD prevalence, whereas serum folate may lack clinical relevance due to susceptibility to confounding factors. RBC folate, as a stable biomarker of long-term folate status, may serve as a superior indicator for investigating folate-MASLD associations.

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Publication Details

Journal
Frontiers in Physiology
Published
2025-03-20
DOI
https://doi.org/10.3389/fphys.2025.1494863
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Elevated red blood cell folate levels are associated with metabolic dysfunction-associated steatotic liver disease: results from NHANES 2017–2020

Yu Song, Ruyue Zhang, Yu Ke, Lin Wang et al.
Frontiers in Physiology
Liver Disease Diagnosis and Treatment
article

Elevated red blood cell folate levels are associated with metabolic dysfunction-associated steatotic liver disease: results from NHANES 2017–2020

Yu Song, Ruyue Zhang, Yu Ke, Lin Wang, Xin Liao
article en

Abstract

These findings suggest that elevated RBC folate levels are independently associated with MASLD prevalence, whereas serum folate may lack clinical relevance due to susceptibility to confounding factors. RBC folate, as a stable biomarker of long-term folate status, may serve as a superior indicator for investigating folate-MASLD associations.

Frontiers in PhysiologyVol. 16
Chengdu Medical College (CN), Third People's Hospital of Chengdu (CN)
Good health and well-being
Openalex Percentile: Top 92%
Liver Disease Diagnosis and Treatment
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