Short-Term Diagnostic Follow-Up of Patients Undergoing Cholecystectomy for Development of Colorectal Cancer

Background: Colorectal cancer (CRC) incidence is increasing globally, imposing considerable pressure on healthcare systems.The prevalence of colorectal cancer in several studies throughout different areas of Pakistan ranged from 4% to 6%, with an overall incidence of 5%.Cholecystectomy, a prevalent surgical intervention, may result in enduring biochemical alterations, heightening intestinal exposure to bile acids and salts, hence elevating the chance of colorectal cancer (CRC).The incidence of colorectal cancer (CRC) among cholecystectomy patients is 119 per 100,000 person-years, in contrast to 86 per 100,000 person-years for those who did not have the surgery.Objective: We intended to monitor individuals undergoing cholecystectomy for two years to assess the incidence of future colorectal cancer. Methodology:This was retrospective research undertaken in the Radiology Department of Fauji Foundation Hospital, Rawalpindi.Imaging and histology records of patients from January 2019 to December 2021 were examined using the Medix online reporting system.Patients who had cholecystectomy were monitored for radiological and histological indications of colorectal cancer during a short-term period of two years.Results: A total of 370 patients were included, with a predominantly female population (98.1%).The highest proportion of patients (47.6%) was in the 41-50 years age group.Over the two-year follow-up period, no cases of colorectal cancer were detected through imaging or histopathology.The study suggests no short-term association between cholecystectomy and colorectal cancer. Conclusion:Cholecystectomy is not associated with the short-term development of colorectal cancer.