Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood

Distal femoral non-union presents significant challenges, often requiring complex treatment strategies to achieve bone healing. In this case, a young male patient with an open fracture of the distal femur developed an atrophic non-union, 9 months after initial fixation. The patient underwent surgical intervention with debridement, leading to a 2.2 cm bone defect and placement of a cylindrical synthetic bone graft (b.Bone), combined with bone marrow aspirate concentrate. This approach aimed to provide structural support and enhance biological healing. The choice of the cylindrical graft was due to its optimal fit and support for the anterior femoral cortex. Postoperative outcomes were favourable, with successful bone healing, confirmed radiologically, and restoration of function. This case demonstrates the potential of synthetic bone substitutes augmented with biological agents as a promising alternative to traditional grafts in managing complex non-unions.

Authors

Institutions

Publication Details

Journal
BMJ Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1136/bcr-2024-264131
Citations
3
Primary Topic
Orthopaedic implants and arthroplasty
Type
article
Field-Weighted Citation Impact
6.02
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood

Charalampos Pitsilos, Peter Vasilios Giannoudis
3 citations
BMJ Case Reports
Orthopaedic implants and arthroplasty
6.02
article

Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood

Charalampos Pitsilos, Peter Vasilios Giannoudis
article en
3 citations

Abstract

Distal femoral non-union presents significant challenges, often requiring complex treatment strategies to achieve bone healing. In this case, a young male patient with an open fracture of the distal femur developed an atrophic non-union, 9 months after initial fixation. The patient underwent surgical intervention with debridement, leading to a 2.2 cm bone defect and placement of a cylindrical synthetic bone graft (b.Bone), combined with bone marrow aspirate concentrate. This approach aimed to provide structural support and enhance biological healing. The choice of the cylindrical graft was due to its optimal fit and support for the anterior femoral cortex. Postoperative outcomes were favourable, with successful bone healing, confirmed radiologically, and restoration of function. This case demonstrates the potential of synthetic bone substitutes augmented with biological agents as a promising alternative to traditional grafts in managing complex non-unions.

BMJ Case ReportsVol. 18(3)
University of Leeds (GB), Leeds Beckett University (GB)
Openalex Percentile: Top 5%
Orthopaedic implants and arthroplasty
6.02
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood — Charalampos Pitsilos, Peter Vasilios Giannoudis · BMJ Case Reports (2025) | TGRS Research Map | TGRS