Office based PRP treatment for obstructive sleep apnea: efficacy and safety evaluation

Background: Many individuals across the globe suffer from obstructive sleep apnea (OSA), a common medical disorder that may have serious physiological and psychological repercussions. Objectives: The purpose of this research is to investigate the effects of injecting platelet-rich plasma into the soft palate as a novel therapeutic strategy for snoring and obstructive sleep apnea. Patients and Methods: This research included forty patients from the Department of Otorhinolaryngology-Head & Neck Surgery at Benha Universities. Patients must be older than 18, of both sexes, and under 60. persons with a BMI below 35 kg/m2 who have moderate to severe OSAS. Results: After surgery, this novel method improved cephalometric parameters like the retroplatal A-P diameter in mm from 6.59 ± 2.25 to 8.26 ± 2.71, improved polysomnogrhic measures like the apnea-hypopnea index (AHI) from 12.93 ± 3.97 to 7.47 ± 3.60, and improved ESS from 10.53 ± 3.93 to 5.67 ± 3.74. Conclusion: For those with moderate to severe OSA symptoms caused by retropalatal collapse, office-based PRP treatment is a safe and well-tolerated therapeutic alternative. It aids in lowering respiratory parameters and subjective OSA symptoms.