Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study
This study demonstrates that TEW scatter correction increases the accuracy of <sup>166</sup>Ho-SPECT images compared to DEW, and we henceforth recommend adopting this method in the clinical <sup>166</sup>Ho-dosimetry workflow. Scanner hardware has a substantial impact on the characteristics of the acquired data, and identical reconstruction settings will therefore not automatically lead to harmonized image quality.
Authors
- Daphne M. V. de Vries–Huizing (ORCID: https://orcid.org/0000-0003-1967-8148)
- Martina Stella (ORCID: https://orcid.org/0000-0001-9794-3184)
- Mette K. Stam (ORCID: https://orcid.org/0009-0004-2843-1854)
- Roel Wierts (ORCID: https://orcid.org/0000-0002-9955-8754)
- Berlinda J. de Wit–van der Veen (ORCID: https://orcid.org/0000-0002-7860-2904)
- Petra Dibbets‐Schneider (ORCID: https://orcid.org/0000-0003-0538-8270)
- Daphne Lobeek (ORCID: https://orcid.org/0000-0003-1282-0826)
- Rob van Rooij (ORCID: https://orcid.org/0000-0001-8546-8283)
- Floris H. P. van Velden (ORCID: https://orcid.org/0000-0003-2859-2119)
- Lovisa E. L. Westlund Gotby (ORCID: https://orcid.org/0000-0002-1059-6616)
- Erik-Jan Rijkhorst
- Camille D. E. Van Speybroeck
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Radboud Institute for Molecular Life Sciences (NL)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s40658-025-00733-8
- Citations
- 2
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- European Commission
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek