Clinical prognostic factors in patients with acute thalamic hemorrhage at Bach Mai hospital

Objectives: To describe the clinical characteristics and identify selected prognostic factors in patients with acute thalamic hemorrhage at Bach Mai Hospital. Subjects and Methods: This study included patients with spontaneous thalamic hemorrhage who were hosspitalized at the Department of Neurology, Bach Mai Hospital, from June 2022 to June 2023. Results: Older patients (≥65 years) had a significantly lower rate of favorable progression compared to younger patients (<65 years) (OR = 0.21, 95% CI: 0.1-0.46). Mean systolic, diastolic blood pressure and body temperature were significantly higher in the unfavorable progression groupp = 0.039, p = 0.004, p = 0.002 < 0.05, respectively). Patients with a Glasgow Coma Scale (GCS) score of ≤8 at admission exhibited a significantly higher rate of unfavorable progression (86.67%) compared to those with a GCS score >8 (26.4%). The rate of unfavorable progression was significantly higher in patients with severe motor weakness (47.76%) compared to those with mild or no paralysis (19.18%). Patients without pupillary abnormalities were 8.86 times more likely to experience favorable disease progression compared to those with pupillary abnormalities. Conclusion: Age, systolic blood pressure, diastolic blood pressure, temperature, Glasgow Coma Scale score, level of muscle strength, and pupillary abnormalities all showed statistically significant differences between the unfavorable and favorable progression groups.