Aspirin Boosts Immune Response to Stop Cancer Spread
A new study in mice shows that COX-1 inhibitors, such as aspirin, block a platelet-mediated pathway that cancer cells use to evade immune detection and spread to other tissues. By reducing TXA2 production, aspirin enhances T-cell activity, leading to fewer metastases in the lungs and liver—a finding that could inform treatment.
Publication Details
- Journal
- Cancer Discovery
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1158/2159-8290.cd-nw2025-0022
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00