Comparison of 68Ga-FAPI-04 PET/CT and 18F-FDG PET/CT in Evaluating Lesion Stages in Constrictive Pericarditis

Constrictive pericarditis, an uncommon cause of diastolic heart failure, is reversible if identified and treated promptly and appropriately. The treatment approach may vary significantly depending on the disease stage of constrictive pericarditis. Here, we report a case of 18 F-FDG and 68 Ga-FAPI-04 PET/CT imaging in a 70-year-old woman with chronic constrictive pericarditis. The thickened pericardium showed mild uptake of 18 F-FDG but intense uptake of 68 Ga-FAPI-04, indicating that the lesion was at the fibrotic phase. This case suggests a promising role of combination of 18 F-FDG and 68 Ga-FAPI PET/CT in accurately and timely assessing the lesion stage in constrictive pericarditis.