Establishment and characterization study of ovine mammary organoids
This study establishes a protocol for the isolation, culture, characterization, and genetic manipulation of ovine MaOs. These organoids serve as a physiologically relevant model for studying the regulatory mechanisms of lactation and mastitis in sheep, providing a tool for future research in veterinary and agricultural sciences.
Authors
- Chao Bian (ORCID: https://orcid.org/0000-0001-9904-721X)
- Ruixue Bai
- Lequn Wang (ORCID: https://orcid.org/0000-0003-3285-2235)
- Xiaohu Su (ORCID: https://orcid.org/0000-0002-3802-6025)
- Chunwei Wang (ORCID: https://orcid.org/0000-0001-8093-9058)
- Sijia Ma (ORCID: https://orcid.org/0000-0002-3978-4346)
- P. Shou
- Zhong Zheng (ORCID: https://orcid.org/0000-0001-5961-2122)
- Liguo Zhang (ORCID: https://orcid.org/0000-0001-7346-8964)
- Quanzhong Xu
- Rui Feng (ORCID: https://orcid.org/0000-0001-9755-8884)
- Y. S. Zhu
- Jingru Ning
- Sarengele
Institutions
- Inner Mongolia University (CN)
- Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences (CN)
- Inner Mongolia People's Hospital (CN)
- Research Institute of Animal Husbandry (MN)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s12917-025-04657-4
- Citations
- 2
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China