Bone and Joint Infection Caused by Clindamycin and Penicillin-G Resistant, Toxigenic

Abstract Corynebacterium diphtheriae, C. ulcerans, and C. tuberculosis are the three species belonging to the diphtheriae complex. C. While C. diphtheriae infections are becoming rare in developed countries, thanks to vaccination, C. ulcerans and C. pseudotuberculosis infections still are rare but increase and are often caused by contact with domestic animals. It should be noted, however, that vaccination protects against diphtheria toxin-producing strains. Here we report an uncommon case of bone and joint infection caused by toxigenic Corynebacterium ulcerans resistant to both clindamycin and penicillin G, in a vaccinated patient. This patient owned a dog whose samples showed carriage of toxigenic C. ulcerans.