Long-term outcomes of pharmacotherapy in patients with persistent postural-perceptual dizziness

The long-term efficacy and safety of serotonergic antidepressants were demonstrated in patients with PPPD. However, somatosensory hypersensitivity, which is sometimes observed as a clinical feature in patients with PPPD, did not improve after pharmacotherapy. Developing treatments to reduce hypersensitivity may improve treatment outcomes.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-03-19
DOI
https://doi.org/10.3389/fneur.2025.1566898
Citations
3
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
2.53
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article

Long-term outcomes of pharmacotherapy in patients with persistent postural-perceptual dizziness

Shuji Izumi, Shinsuke Ohshima, Arata Horii, Ryota Kai et al.
3 citations
Frontiers in Neurology
Vestibular and auditory disorders
2.53
article

Long-term outcomes of pharmacotherapy in patients with persistent postural-perceptual dizziness

Shuji Izumi, Shinsuke Ohshima, Arata Horii, Ryota Kai, Chihiro Yagi, Tatsuya Yamagishi, Akira Kimura
article en
3 citations

Abstract

The long-term efficacy and safety of serotonergic antidepressants were demonstrated in patients with PPPD. However, somatosensory hypersensitivity, which is sometimes observed as a clinical feature in patients with PPPD, did not improve after pharmacotherapy. Developing treatments to reduce hypersensitivity may improve treatment outcomes.

Frontiers in NeurologyVol. 16
Niigata University (JP)
Openalex Percentile: Top 12%
Vestibular and auditory disorders
2.53
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