Brain injury, endocrine disruption, and immune dysregulation in HIV-positive men who have sex with men with late HIV diagnosis
This study suggests that LD may contribute to brain injury, endocrine disruption, and immune dysregulation in HIV-positive MSM. Consequently, there is an urgent need to develop public health strategies targeting late diagnosis, with a focus on strengthening screening and early detection for high-risk populations, as well as monitoring brain injury, endocrine, and immune functions in individuals with LD, and formulating precise, individualized intervention strategies to reduce the long-term impact of LD on the health of HIV-positive MSM.
Authors
- Guixin Sun (ORCID: https://orcid.org/0000-0002-0962-8561)
- Miaotian Cai
- Rui Wang (ORCID: https://orcid.org/0009-0004-8149-3173)
- Tong Zhang (ORCID: https://orcid.org/0000-0002-8838-4963)
- Yundong Ma
- Lei Wang (ORCID: https://orcid.org/0000-0003-0825-3494)
- Meixin Ren
- Yang Zhang (ORCID: https://orcid.org/0009-0008-3577-6286)
- Yihui He
- Hao Liu (ORCID: https://orcid.org/0000-0002-2366-9554)
Institutions
- Capital Medical University (CN)
- Beijing Anding Hospital (CN)
- Beijing YouAn Hospital (CN)
- Beijing Center for Disease Prevention and Control (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1436589
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China