Cladribine Is Associated With Stable Cortical Gray Matter Lesion Burden in Multiple Sclerosis: A 7T MRI Study

These observational data suggest that cladribine therapy stabilizes cortical demyelination in MS over the first year of treatment. Overall, LME burden remained stable over 1 year; however, within-subject resolution and accrual were noted.

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Publication Details

Journal
Journal of Neuroimaging
Published
2025-03-01
DOI
https://doi.org/10.1111/jon.70032
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Cladribine Is Associated With Stable Cortical Gray Matter Lesion Burden in Multiple Sclerosis: A 7T MRI Study

Renxin Chu, Maria K. Houtchens, Shahamat Tauhid, Youmna Jalkh et al.
2 links
Journal of Neuroimaging
Multiple Sclerosis Research Studies
article

Cladribine Is Associated With Stable Cortical Gray Matter Lesion Burden in Multiple Sclerosis: A 7T MRI Study

Renxin Chu, Maria K. Houtchens, Shahamat Tauhid, Youmna Jalkh, Syed Rizvi, Brian C. Healy, Rohit Bakshi, Farrah Jasmine Mateen, Jonathan Zurawski, Samar Khalil, Molly Quattrucci, Tarun Singhal, Salvatore Napoli
article en

Abstract

These observational data suggest that cladribine therapy stabilizes cortical demyelination in MS over the first year of treatment. Overall, LME burden remained stable over 1 year; however, within-subject resolution and accrual were noted.

Journal of NeuroimagingVol. 35(2)
Brigham and Women's Hospital (US), Harvard University (US), Brown University (US), Massachusetts General Hospital (US), New England Center for Children (US)
EMD Serono
Good health and well-being
Openalex Percentile: Top 93%
Multiple Sclerosis Research Studies
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