Advances in the molecular mechanisms of exercise biomechanics for interventions in adolescent obesity

The global epidemic of adolescent obesity is becoming increasingly severe, posing significant threats to both the physical health of adolescents and their psychological well-being and social adaptability. Exercise biomechanics, as an interdisciplinary field that integrates biology, mechanics, physics, and medicine, focuses on examining the mechanical behavior of organisms during physical activity and its implications for physiological and pathological processes. This paper aims to provide a comprehensive review of recent advancements in the research on molecular mechanisms related to exercise biomechanics in the context of adolescent obesity intervention to offer scientific theoretical support for the prevention and treatment of obesity. In recent years, researchers have elucidated the impact of exercise interventions on the expression and signaling of obesity-related genes by modulating critical pathways, including fat metabolism, inflammatory responses, and insulin sensitivity. This has been achieved through the application of advanced technologies such as high-throughput sequencing, proteomics, and metabolomics, thereby providing molecular-level insights into the mechanisms by which exercise contributes to the prevention and treatment of obesity in adolescents. Building upon this foundation, the present paper aims to further investigate future research directions and the potential applications of exercise biomechanics to enhance the optimization and development of intervention strategies for adolescent obesity.