Associations between brominated flame retardants, including polybrominated diphenyl ethers, and immune responses among women in the California Teachers Study
Two BFR congeners were statistically associated with altered levels of circulating immune markers involved in B cell activation pathways; replication and further evaluation of these novel associations are warranted. If confirmed, our results add to the current literature regarding possible immune mechanisms by which BFR exposures contribute to immune-related health endpoints and conditions where B cell activation is prominent, including autoimmune conditions.
Authors
- Peggy Reynolds (ORCID: https://orcid.org/0000-0002-5783-7536)
- Larry Magpantay (ORCID: https://orcid.org/0000-0002-6322-2474)
- Sophia Wang (ORCID: https://orcid.org/0000-0003-2597-9393)
- Debbie E. Goldberg (ORCID: https://orcid.org/0009-0008-0428-2769)
- Emma S. Spielfogel (ORCID: https://orcid.org/0000-0002-9006-239X)
- Julie Von Behren (ORCID: https://orcid.org/0000-0002-9342-5299)
- Pramod Regmi (ORCID: https://orcid.org/0000-0003-0226-3894)
- Priyanthi S. Dassanayake
- Marta Epeldegui (ORCID: https://orcid.org/0000-0002-7605-5994)
- Otoniel Martı́nez-Maza (ORCID: https://orcid.org/0000-0003-1364-0675)
- Emily Cauble (ORCID: https://orcid.org/0000-0002-3119-4106)
- James V. Lacey (ORCID: https://orcid.org/0000-0002-4560-8592)
- Daniel Blyakher
Institutions
- University of California, Los Angeles (US)
- University of California, San Francisco (US)
- Black AIDS Institute (US)
- City of Hope (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Frontiers in Epidemiology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fepid.2025.1452934
- Citations
- 4
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 4.80