Asymmetrical glymphatic dysfunction in patients with long Covid associated neurocognitive impairment- correlation with BBB disruption
Our study indicates that disordered para vascular drainage, a marker for glymphatic system and BBB damage may contribute to neurocognitive impairment (NCI) among patients with PASC. The DTI-ALPS index, which does not require contrast injection, has the potential to serve as a non-invasive biomarker.
Authors
- Joga Chaganti (ORCID: https://orcid.org/0000-0003-4776-5038)
- Bruce J. Brew (ORCID: https://orcid.org/0000-0003-0622-1392)
- Tanush K. Talekar
Institutions
- Thomas Jefferson University (US)
- Thomas Jefferson University Hospital (US)
- UNSW Sydney (AU)
- St Vincent's Hospital Sydney (AU)
- Imaging Center (US)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s12883-025-04133-4
- Citations
- 5
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 4.55