Immunotherapy yields breed-specific worst survival outcomes among three investigated therapies in French bulldogs with high-grade glioma
This study provides evidence for an immunotherapy-resistant form of HGG in French bulldogs, suggesting that the breed harbors key molecular differences affecting the tumor and tumor-immune microenvironment and subsequent poor response to treatment.
Authors
- Walter C. Low (ORCID: https://orcid.org/0000-0001-8593-0175)
- G. Elizabeth Pluhar (ORCID: https://orcid.org/0000-0002-7881-5061)
- Katherine Hansen (ORCID: https://orcid.org/0000-0001-5500-287X)
- Amanda R. Taylor (ORCID: https://orcid.org/0000-0003-1971-2764)
- Susan A. Arnold (ORCID: https://orcid.org/0000-0002-4081-1145)
- Vijay Agarwal
Institutions
- Albert Einstein College of Medicine (US)
- University of Minnesota (US)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fvets.2025.1532439
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63