Spinal hypermobility accelerates ossification in posterior longitudinal ligaments: insights from an in vivo mouse model
spinal hypermobility promotes the progression of ossification in mice with heterotopic ossification of the spine, shedding new light on the pathogenesis of OPLL.
Authors
- Hongkun Chen (ORCID: https://orcid.org/0000-0003-3173-6953)
- Tao Tang (ORCID: https://orcid.org/0000-0002-4863-6660)
- Zhiyu Zhou (ORCID: https://orcid.org/0000-0002-8101-2083)
- Zhengya Zhu (ORCID: https://orcid.org/0000-0002-9250-4251)
- Fuan Wang (ORCID: https://orcid.org/0000-0002-3063-2485)
- Jianmin Wang (ORCID: https://orcid.org/0000-0001-9531-3103)
- Zhongyuan He (ORCID: https://orcid.org/0000-0002-6194-0720)
- Lin Chen (ORCID: https://orcid.org/0000-0002-5847-2989)
- Jianfeng Li (ORCID: https://orcid.org/0000-0002-3243-8539)
- Yunfeng Yao
- Jiaxiang Zhou
- Shaoyu Liu (ORCID: https://orcid.org/0000-0003-2824-8780)
- Xizhe Liu (ORCID: https://orcid.org/0000-0002-5658-3626)
Institutions
- Qingdao University (CN)
- Sun Yat-sen University (CN)
- Xuzhou Medical College (CN)
- Dalian Medical University (CN)
- Anhui Medical University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Affiliated Hospital of Qingdao University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fphys.2025.1561199
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 0.00