Oropharyngeal carcinomas induce circulating monocytes to express a TAM-like pro-tumor expression profile that suppresses T-cell proliferation
Targeting the early transition of monocytes into pro-tumor TAMs could be used to develop new therapies for OPC.
Authors
- Arnon Arazi
- Douglas K. Frank (ORCID: https://orcid.org/0000-0002-3711-5149)
- Nagashree Seetharamu (ORCID: https://orcid.org/0000-0002-3282-7622)
- Vincent R. Bonagura (ORCID: https://orcid.org/0000-0002-0681-2099)
- Christopher Papayannakos
- Dev Kamdar (ORCID: https://orcid.org/0000-0002-0481-3397)
- Bettie M. Steinberg (ORCID: https://orcid.org/0000-0003-2372-8099)
- James A. DeVoti
- Mohd Israr
- Lucio M. Pereira
- F. Lam
Institutions
- Northwell Health (US)
- Feinstein Institute for Medical Research (US)
- Hofstra University (US)
- Long Island Jewish Medical Center (US)
- Cohen Children's Medical Center (US)
- North Shore Diabetes and Endocrine Associates (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1539780
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80