AAV-mediated transduction of songbird retina

The consistently high and photoreceptor-specific transduction efficiency makes the AAV2/9 serotype a powerful tool for carrying out genetic manipulations in avian retinal photoreceptors, thus opening a wealth of opportunities to investigate physiological aspects underlying retinal processing in birds, such as physiological recordings and/or post-transductional behavioural readouts for future vision-related research.

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Publication Details

Journal
Frontiers in Physiology
Published
2025-03-19
DOI
https://doi.org/10.3389/fphys.2025.1549585
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

AAV-mediated transduction of songbird retina

Ezequiel Mendoza, Katrin Haase, Constance Scharff, Henrik Mouritsen et al.
Frontiers in Physiology
Retinal Development and Disorders
article

AAV-mediated transduction of songbird retina

Ezequiel Mendoza, Katrin Haase, Constance Scharff, Henrik Mouritsen, Dominik Heyers, Isabelle Musielak, Karin Dedek, Karl‐Wilhelm Koch, Regina Feederle, Pranav Kumar Seth, Baladev Satish, Lisa Borowsky
article en

Abstract

The consistently high and photoreceptor-specific transduction efficiency makes the AAV2/9 serotype a powerful tool for carrying out genetic manipulations in avian retinal photoreceptors, thus opening a wealth of opportunities to investigate physiological aspects underlying retinal processing in birds, such as physiological recordings and/or post-transductional behavioural readouts for future vision-related research.

Frontiers in PhysiologyVol. 16
Carl von Ossietzky Universität Oldenburg (DE), University of Sussex (GB), Helmholtz Zentrum München (DE), Freie Universität Berlin (DE)
Openalex Percentile: Top 95%
Retinal Development and Disorders
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