Insights into the effects of apelin-13 on renal function and NHE3 activity following ischemia/reperfusion-induced acute kidney injury
The overall findings suggest that apelin-13 suppresses tubular proliferation and potentially impairs the adaptive response to renal I/R injury, thereby highlighting its relevance in ischemia-induced AKI.
Authors
- Juliana da Costa Santos Pessoa (ORCID: https://orcid.org/0000-0002-1167-249X)
- Mariana Charleaux de Ponte
- Maria Oliveira‐Souza (ORCID: https://orcid.org/0000-0003-0946-9377)
- Guilherme Lopes Gonçalves (ORCID: https://orcid.org/0000-0002-0241-6072)
- Heitor Macedo Braz (ORCID: https://orcid.org/0009-0002-4400-7231)
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fphys.2025.1544274
- Citations
- 2
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Conselho Nacional de Desenvolvimento Científico e Tecnológico