MIDBRAIN INFARCTION WITH INTERNUCLEAR OPHTHALMOPLEGIA: A RARE PRESENTATION

Internuclear ophthalmoplegia (INO) is a distinctive ocular motility disorder caused by damage to the medial longitudinal fasciculus (MLF), often due to ischemic stroke. We report the case of a 67-year-old male presenting with INO due to an acute midbrain infarction. The patient exhibited adduction deficit in the left eye with abduction nystagmus in the right eye, gait ataxia, slurred speech, and intentional tremors. INO results from MLF disruption and is commonly associated with cerebrovascular accidents. MRI findings confirmed midbrain infarction as the underlying pathology. Midbrain infarction causing Internuclear ophthalmoplegia is usually very rare presentation. Very few cases have been reported in literature. Our case reported below is one such rare presentation. This case underscores the importance of considering midbrain infarction as a cause of INO, particularly in patients with significant vascular risk factors. Detailed clinical examination and neuroimaging are essential for accurate diagnosis and management.

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Journal
INDIAN JOURNAL OF APPLIED RESEARCH
Published
2025-03-01
DOI
https://doi.org/10.36106/ijar/3402932
Primary Topic
Ophthalmology and Eye Disorders
Type
article
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article

MIDBRAIN INFARCTION WITH INTERNUCLEAR OPHTHALMOPLEGIA: A RARE PRESENTATION

A. Venkat Nikhil, Sujana Gogineni, Kotagiri Vamsi Krishna, K. Dhanus
INDIAN JOURNAL OF APPLIED RESEARCH
Ophthalmology and Eye Disorders
article

MIDBRAIN INFARCTION WITH INTERNUCLEAR OPHTHALMOPLEGIA: A RARE PRESENTATION

A. Venkat Nikhil, Sujana Gogineni, Kotagiri Vamsi Krishna, K. Dhanus
article en

Abstract

Internuclear ophthalmoplegia (INO) is a distinctive ocular motility disorder caused by damage to the medial longitudinal fasciculus (MLF), often due to ischemic stroke. We report the case of a 67-year-old male presenting with INO due to an acute midbrain infarction. The patient exhibited adduction deficit in the left eye with abduction nystagmus in the right eye, gait ataxia, slurred speech, and intentional tremors. INO results from MLF disruption and is commonly associated with cerebrovascular accidents. MRI findings confirmed midbrain infarction as the underlying pathology. Midbrain infarction causing Internuclear ophthalmoplegia is usually very rare presentation. Very few cases have been reported in literature. Our case reported below is one such rare presentation. This case underscores the importance of considering midbrain infarction as a cause of INO, particularly in patients with significant vascular risk factors. Detailed clinical examination and neuroimaging are essential for accurate diagnosis and management.

INDIAN JOURNAL OF APPLIED RESEARCH
Siddhartha Medical College (IN)
Openalex Percentile: Top 93%
Ophthalmology and Eye Disorders
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