Impact of statin use on short- and long-term outcomes in patients with sepsis-induced myocardial injury: insights from the MIMIC-IV database
Our study demonstrates that statin use is significantly associated with reduced mortality in SIMI patients across 28 days, 90 days, and 1 year. Simvastatin provides substantial benefits, with low-dose statins providing greater advantages compared to high-dose formulations.
Authors
- Gengzhen Yao
- Mengyi Wu
- Pingping Niu (ORCID: https://orcid.org/0000-0001-9350-4416)
- Xu Zou (ORCID: https://orcid.org/0000-0002-6489-6227)
- Weihui Lu (ORCID: https://orcid.org/0000-0001-7754-2682)
- John Jing-Wei Chen (ORCID: https://orcid.org/0000-0003-3644-7528)
- Yuan Liu (ORCID: https://orcid.org/0000-0001-6227-024X)
- Ying Yuan (ORCID: https://orcid.org/0000-0002-2706-9177)
- B. Shang (ORCID: https://orcid.org/0009-0007-9975-1822)
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-19
- DOI
- https://doi.org/10.3389/fphar.2025.1520107
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01