Bioanalytical method validation to quantify ketorolac in human vitreous and aqueous via surrogate matrix of human plasma
The validated method can use plasma as a surrogate matrix for quantitation of ketorolac in aqueous and vitreous humor, thereby eliminating the need to procure human vitreous and aqueous samples for validation prior to initiation of a clinical trial.
Authors
- Neelanjan Bose (ORCID: https://orcid.org/0000-0002-3817-4757)
- Prajita Pandey (ORCID: https://orcid.org/0000-0002-9675-2770)
- Ana Najafi
- Bernadette White (ORCID: https://orcid.org/0000-0001-7016-7429)
- Ramin Najafi
- Ryan K. Cheu
- Colin Goswell
- Sara Butterworth Connell (ORCID: https://orcid.org/0000-0001-8320-8496)
- Nicolee Schulze
- Jim Nevelos
Institutions
- Battelle (US)
- Bellevue Hospital Center (US)
- Rayner (United States) (US)
- Emery Oleochemicals (Malaysia) (MY)
Publication Details
- Journal
- Future Science OA
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1080/20565623.2025.2476866
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71