Identification of variants in exon 4 of the LDLR gene and assessment of their effects on the produced proteins in saudi women with metabolic syndrome
Four variants in the LDLR gene, exon 4 (2 missense and 2 nonsense variants) have been identified and their expected structural effects were assessed in Saudi Arabian women with MetS in Makkah region.
Authors
- Mohiuddin M. Taher (ORCID: https://orcid.org/0000-0003-3044-3809)
- Nazik Altayeb Abdelbasit
- Maowia M. Mukhtar (ORCID: https://orcid.org/0000-0003-2183-5915)
- Abdallah M. Gameel (ORCID: https://orcid.org/0000-0003-4632-015X)
- Ayman Saber Mohamed (ORCID: https://orcid.org/0000-0003-3975-4355)
- Shimaa Abdelsattar (ORCID: https://orcid.org/0000-0002-3993-5378)
- Sameer H. Fatani
- Hiba S. Al-Amodi
- Hala F. M. Kamel
Institutions
- Ain Shams University (EG)
- Cairo University (EG)
- University of Khartoum (SD)
- Umm al-Qura University (SA)
- National University (SD)
- Children Cancer Hospital (EG)
- Menoufia University (EG)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1186/s13098-025-01650-7
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00