Exploring an innovative augmentation strategy in spinal fusion: A novel selective prostaglandin EP4 receptor agonist as a potential osteopromotive factor to enhance lumbar posterolateral fusion
KMN-159 emerges as a novel osteopromotive factor, coupled with its functionalized MCM scaffold presents a potential bioactive material for enhancing PLF surgery outcomes.
Authors
- Lisa Findeisen
- Hartmut Kern (ORCID: https://orcid.org/0000-0002-1114-1066)
- Xinggui Tian (ORCID: https://orcid.org/0000-0003-3619-3943)
- Deepak Raina (ORCID: https://orcid.org/0000-0001-8767-892X)
- Stefan Zwingenberger (ORCID: https://orcid.org/0000-0002-1831-3035)
- Alexander C. Disch (ORCID: https://orcid.org/0000-0001-8414-4041)
- Robert Gottwald
- Klaus‐Dieter Schaser (ORCID: https://orcid.org/0000-0002-8492-5646)
- Corina Vater (ORCID: https://orcid.org/0000-0002-3160-2800)
- Anja Winkler (ORCID: https://orcid.org/0000-0002-8854-7726)
- Lucas-Maximilian Matuszewski (ORCID: https://orcid.org/0000-0002-3324-8999)
- Niels Modler (ORCID: https://orcid.org/0000-0003-2834-8933)
- Julia Bolte (ORCID: https://orcid.org/0000-0002-2930-8274)
- Lutz Straßburger (ORCID: https://orcid.org/0000-0003-4661-6540)
Institutions
- Lund University (SE)
- University Hospital Carl Gustav Carus (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Biomaterials
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1016/j.biomaterials.2025.123278
- Citations
- 4
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.89