Base‐Promoted [4 + 2] Annulation for the Synthesis of Tri‐Aryl Substituted <i>α</i>‐Pyrones
A transition‐metal‐free procedure for synthesizing tri‐aryl substituted α ‐pyrones has been developed. It involves conjugate addition, CO bond formation, and CO bond cleavage. This procedure provides an efficient protocol for the synthesis of multisubstituted α ‐pyrones from readily available starting materials. Notable features of this program are high atom economy and transition‐metal‐free.
Authors
- Mengdan Wang (ORCID: https://orcid.org/0000-0002-9840-5924)
- Jianyue Li
- Fengmin Wu (ORCID: https://orcid.org/0000-0003-1581-9687)
- Bingli Pan (ORCID: https://orcid.org/0000-0002-2554-822X)
- Kun Liu (ORCID: https://orcid.org/0000-0003-3357-920X)
- Junying Ma (ORCID: https://orcid.org/0000-0002-0641-7291)
- Xiaowei Wang (ORCID: https://orcid.org/0000-0003-0940-1882)
- Junling Wang (ORCID: https://orcid.org/0000-0002-9075-4089)
Institutions
- Henan University of Science and Technology (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1002/ejoc.202401430
- Citations
- 1
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94